Italy is a destination that has it all. If you’re planning a visit, it’s well worth taking the time to leave your luxury vacation rental to explore the wider region. Not sure where to start? Read on to find out the hidden cultural gems of Sicily, Tuscany, Como and Vatican City..

As featured in ‘The White Lotus’, San Domenico Palace is a UNESCO World Heritage site made up of 142 steps and hand-painted tiles. This Four Season Hotel is also home to Principe Cerami – a clifftop restaurant with romantic ocean views. Located in Taormina, take the time to potter around the picturesque town and its bijou shops with cobbled streets. There are many historical landmarks to see including the ancient Greco-Rome theatre of ‘Teatro Antico di Taormina’ and the ‘Piazza IX Aprile’ in the heart of Old Town.

Seafood is the local delicacy, which there’s no escaping in the many cafes and restaurants you’ll encounter. To save room for dessert, the local ‘Biscotti di Mandorla’ is a mouth-watering twist on a lemon-infused cookie.

With more sandy coastline than any other region of Italy, you’re spoilt for choice when it comes to beaches. Taormina remains one of the most popular, or nearby the southern tip of Sampieri Beach is a spectacular spot.

With its rolling hills, Tuscany is filled with beauty at every turn. The village of Volterra is like stepping into a painting with its medieval churches and 16th century buildings to marvel at. Meanwhile the tiny village of Maremma is made for wine aficionados, with vineyard upon vineyard to explore. Take the time to sample the local delights; rustic stews, grilled vegetables, artisan cheese and, of course, pasta.

It would be remiss not to mention the Tuscan capital of Florence. A city built on the foundations of art and culture, it’s (busy roads) are best explored by foot. Be sure to soak up views of ‘Ponte Vecchio’ from Piazzale Michelangelo, a prime photo spot. Ahead of your visit, reserve a table at ‘Enoteca Pinchiorri’ – a three-star Michelin restaurant, considered one of the best in the world. Foodies can also indulge in the local sport of Truffle hunting, or maybe take a helicopter or hot air balloon ride over the region -Firenze Monogolfiere is one of the top operators.

Famous for its lakes, Como’s location has been historically significant in transport and art. Originally conquered by the Romans, it suffered many invasions, each leaving an imprint on it. Today this can be seen pouring out of its gothic architecture and colorful piazzas. Take in the rich history at ‘Archaeological Museum’ and ‘Villa Carlotta’ – a museum with works by Antonio Canova, Francesco Hayez and others – plus its botanical gardens are outstanding.

Of course, the main attraction here is Lake Como itself. From the comfort of your luxury villa rental in the charming town of Bellagio, explore at your leisure, including the ornate ‘Basilica di San Giacomo’ church and bell tower.

Home to the Roman Catholic Church, Vatican City is the place to indulge in iconic art and architecture. At the heart of this is ‘Museo Vaticani’, the largest collection of works of art in the world, including Roman sculptures and Renaissance art masterpieces. Rooms and floors are linked by the noteworthy Spiral Staircase masterminded by Giuseppe Momo.

Naturally, the Sistine Chapel is unmissable, with jaw-dropping works by Michelangelo amongst other world-famous artists. However, hidden gems to look out for include ‘Caravaggio’s Entombment of Christ’, hidden away in a quiet corner and Aldobrandini’s ‘Wedding Fresco’ delving into ancient wedding rites.